Frequency of New-Onset Pathologic Compulsive Gambling or Hypersexuality After Drug Treatment of Idiopathic Parkinson Disease

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Pathological gambling and hypersexuality due to dopaminergic treatment in Parkinson' disease.

INTRODUCTION Prevalence of psychiatric disorders in patients suffering from Parkinson's disease varies from 12 to 90%. The most common disorder in the natural evolution of Parkinson's disease is depression. However, episodes of psychosis and hypomania are related to treatment with L-dopa and dopaminergic agents. Other recognized, although less frequent, psychiatric disorders are hypersexuality ...

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Reports of pathological gambling, hypersexuality, and compulsive shopping associated with dopamine receptor agonist drugs.

IMPORTANCE Severe impulse control disorders involving pathological gambling, hypersexuality, and compulsive shopping have been reported in association with the use of dopamine receptor agonist drugs in case series and retrospective patient surveys. These agents are used to treat Parkinson disease, restless leg syndrome, and hyperprolactinemia. OBJECTIVES To analyze serious adverse drug event ...

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ژورنال

عنوان ژورنال: Mayo Clinic Proceedings

سال: 2009

ISSN: 0025-6196

DOI: 10.4065/84.4.310